Role of endothelial cells in early pancreas and liver development

Ontogenic development of digestive accessory glands in larval and juvenile Vimba bream, Vimba vimba (Pallas, 1814)

The current study investigated histological development and histochemistry of digestive accessory glands of Vimba bream Vimba vimba from hatching through 60th day after hatching (DAH). The samples were randomly taken from day 1 (hatching) until the full absorption of the yolk sac at day 7 and the day after that, then with 2, 5, and 10 days intervals until 60 DAH. The development of the digestiv...

Mentha, Dracocephalum and Propolis effects on the health of Pancreas and Liver cells

Early oleate deficiency leads to severe defects in fetal rat liver development

Objective(s): Oleate can be produced through de novo synthesis, which contributes to biological processes and signaling pathways. However, the role of this non-essential fatty acid in hepatic development remains unclear. The current study aimed to evaluate the influence of early oleate deficiency induced by the inhibitor of de novo oleate synthesis MF-438 on fetal rat ...

Spironolactone Inhibits NADPH Oxidase-Mediated Oxidative Stress and Dysregulation of the Endothelial NO Synthase in Human Endothelial Cells

Accumulating evidence indicates that aldosterone plays a critical role in the mediation of oxidative stress and vascular damage. NADPH oxidase has been recognized as a major source of oxidative stress in vasculature. However, the relation between NADPH oxidase in aldosterone-mediated oxidative stress in endothelial cells remains to be ascertained. The present study aimed to investigate the rel...

بررسی اثر روغن هسته انگور بر هیستوپاتولوژی کبد و پانکراس و لیپیدهای پلاسما در موش‌های صحرایی دیابتی شده با استرپتوزوتوسین

 Background & Aims: Diabetes Mellitus is the most prevalent endocrine diseases causing nephropathy, retinopathy, and cardiovascular complications. Dyslipidemia, acute pancreatic necrosis, and fat metabolism disorders in liver of diabetic patients have been reported. Studies suggest that grape seed oil constitute anti-oxidant activity capable of decreasing serum cholesterol as well as liver tota...